Ann Castelfranco
Associate Researcher

Békésy Laboratory of Neurobiology
Pacific Biosciences Research Center
1993 East-West Road
Honolulu, HI 96822

office: PBRC Rm. 206
phone: 956-6990
fax: 956-6984

email: castelf@pbrc.hawaii.edu

 

Research Description

My research uses mathematical modeling approaches to study the interaction between cellular morphology and computational properties of neurons, including synaptic integration and neuromodulation. A current focus is on the effects of the structure of the "myelin" sheath on impulse conduction in invertebrate neurons.

Selected Publications

1. Castelfranco AM and Hartline DK (2004) Corrections for space-clamp errors in measured parameters of voltage-dependent conductances in a cylindrical neurite. Biol. Cybern. 90:289-290.

2. Hartline DK and Castelfranco AM (2003) Simulations of voltage clamping poorly space-clamped voltage-dependent conductances in a uniform cylindrical neurite. J. Comput. Neurosci. 14:253-269.

3. Castelfranco AM and Hartline DK (2002) Simulations of space-clamp errors in estimating parameters of voltage-gated conductances localized at different electrotonic distances. Neurocomputing 44-46:75-80.

4. Castelfranco AM, Robertson LT and McCollum G (1994) Detail, proportion and foci among face receptive fields of climbing fibers in cat cerebellum. Somatosens. Motor Res. 11:27-46.

Modified March 25, 2006