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In trifluoperizine (TFP), which apparently does not inhibit
endocytosis but does inhibit movement of vesicles away from the
parasomal sacs (ps), coated (cov) and preendosomal
(prev) vesicles and early endosomes (ee) become strongly
labeled with HRP but all remain within the cortex. TFP seems to
interfere with membrane movements into the cell so that even the
products of coated pits arising from early endosomes, the carrier
vesicles, remain in the cortex. EM taken on 10/9/87 by R. Allen with
Zeiss 10A TEM. Neg. 12,000X. Bar = 0.5µm. Published in J. Cell Sci.
101:449-461, 1992.
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